Lymph node yield and lymph node density for elective level II-IV neck dissections in laryngeal squamous cell carcinoma patients

Cayonu M., Tuna E. U., Acar A., Dinc A. S. K., Sahin M. M., Boynuegri S., ...Daha Fazla

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, cilt.276, sa.10, ss.2923-2927, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 276 Sayı: 10
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1007/s00405-019-05560-z
  • Dergi Adı: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2923-2927
  • Anahtar Kelimeler: Lymph node yield, Laryngeal squamous cell carcinoma, Neck dissection, Metastatic lymph node yield, GASTRIC-CANCER, BREAST-CANCER, SURVIVAL, RATIO, HEAD, PREDICTOR, NUMBER, LYMPHADENECTOMY, METASTASES, RESECTION
  • Gazi Üniversitesi Adresli: Evet

Özet

Purpose To determine the minimum lymph node yield (LNY) in patients with laryngeal squamous cell carcinoma (LSCCs). Methods This retrospective study was performed in a tertiary care hospital setting and included 42 LSCC patients aged 39-81 years (females, n = 2; males, n = 40) who underwent a total or partial laryngectomy and elective bilateral level II-IV neck dissections (unilateral neck dissections: n = 84). Results The average LNY in the unilateral level II-IV lymph node dissections was 25.9 +/- 10, and the average metastatic LNY was 0.9 +/- 1.9. The unilateral neck dissections were grouped according to the number of lymph nodes. There was no significant difference between the groups in terms of the metastatic LNY (p = 0.5). The metastatic lymph node density (LND) (metastatic lymph node yield/LNY) was 0.043 for unilateral neck level II-IV neck dissections. A Cox regression analysis revealed no significant relationship between survival and the LNY and LND in bilateral neck dissections (p = 0.4 and p = 0.8, respectively). Conclusions The results revealed no minimum number of lymph nodes that could reliably detect metastatic lymph nodes in LSCC patients.