Bone Morphogenetic Protein Levels in Osteoarthritis
TURKIYE FIZIKSEL TIP VE REHABILITASYON DERGISI-TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION, cilt.60, sa.2, ss.117-120, 2014 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 60 Sayı: 2
- Basım Tarihi: 2014
- Doi Numarası: 10.5152/tftrd.2014.37043
- Dergi Adı: TURKIYE FIZIKSEL TIP VE REHABILITASYON DERGISI-TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.117-120
- Gazi Üniversitesi Adresli: Evet
Özet
Objective: The modern treatment approach for osteoarthritis aims at suppressing the inflammation by antagonizing such proinflammatory cytokines. More complicated approaches are expected to come to the forefront in the future that focus on such signals as bone morphogenetic proteins (BMPs) of the transforming growth factor (TGF)-beta superfamily and alleviate or antagonize the destruction process. These proteins are associated with many cellular functions, such as proliferation, differentiation, and apoptosis. We investigated the BMP levels in the serum and urine samples of patients with osteoarthritis.