Bone Morphogenetic Protein Levels in Osteoarthritis


Bozkurt S., Karasu A. U. , SEPİCİ DİNÇEL A. , Tas N.

TURKIYE FIZIKSEL TIP VE REHABILITASYON DERGISI-TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION, cilt.60, ss.117-120, 2014 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 60 Konu: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5152/tftrd.2014.37043
  • Dergi Adı: TURKIYE FIZIKSEL TIP VE REHABILITASYON DERGISI-TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION
  • Sayfa Sayıları: ss.117-120

Özet

Objective: The modern treatment approach for osteoarthritis aims at suppressing the inflammation by antagonizing such proinflammatory cytokines. More complicated approaches are expected to come to the forefront in the future that focus on such signals as bone morphogenetic proteins (BMPs) of the transforming growth factor (TGF)-beta superfamily and alleviate or antagonize the destruction process. These proteins are associated with many cellular functions, such as proliferation, differentiation, and apoptosis. We investigated the BMP levels in the serum and urine samples of patients with osteoarthritis.