Zeaxanthin and ocular health, from bench to bedside

Manikandan R., Thiagarajan R., Goutham G., Arumugam M., Beulaja M., Rastrelli L., ...Daha Fazla

FITOTERAPIA, cilt.109, ss.58-66, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 109
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.fitote.2015.12.009
  • Dergi Adı: FITOTERAPIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.58-66
  • Anahtar Kelimeler: Age-related macular degeneration, Cataract, Ocular problems, Oxidative stress, Zeaxanthin, MACULAR PIGMENT, DIETARY CAROTENOIDS, BETA-CAROTENE, LUTEIN, CATARACT, RISK, DAMAGE, SERUM, ANTIOXIDANTS, BIOACCESSIBILITY
  • Gazi Üniversitesi Adresli: Evet

Özet

Cataracts, glaucoma, and age-related macular degeneration are knownas major ocular problems which cause blindness among the elderly population worldwide. Oxidative stress plays an important role in both the initiation and progression of ocular problems and with respect to this; dietary antioxidants can serve as a therapeutic strategy for the improvement of ocular health. Zeaxanthin is known as one of the most important and common xanthophyll carotenoids, possessing multiple therapeutic effects such as strong antioxidant and pro-oxidant behaviour as well as anti-inflammatory effects. A growing body of literature shows that zeaxanthin mitigates ocular problems and suppresses oxidative stress in the Tetinal tissues. This paper aims to critically review the available literature regarding the beneficial effects of zeaxanthin on ocular problems with emphasis on its chemistry, bioavailability, and sources. (C) 2015 ElsevierB.V. All rights reserved.