Expression of Cyclooxygenase-2, 12-Lipoxygenase, and Inducible Nitric Oxide Synthase in Head and Neck Squamous Cell Carcinoma

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Celenk F., BAYRAMOĞLU İ., Yilmaz A., Menevse A., Bayazit Y.

JOURNAL OF CRANIOFACIAL SURGERY, vol.24, no.4, pp.1114-1117, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 24 Issue: 4
• Publication Date: 2013
• Doi Number: 10.1097/scs.0b013e31828f2491
• Journal Name: JOURNAL OF CRANIOFACIAL SURGERY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1114-1117
• Keywords: Head and neck cancer, inflammation, larynx cancer, cyclooxygenase-2, 12-lipoxygenase, inducible nitric oxide synthase, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, ARACHIDONIC-ACID METABOLISM, ENDOTHELIAL GROWTH-FACTOR, TUMOR ANGIOGENESIS, CANCER, INHIBITION, INFLAMMATION, CARCINOGENESIS, PROSTAGLANDINS, LIPOXYGENASES
• Gazi University Affiliated: Yes

Abstract

Aim: The objective of this study was to investigate whether cyclooxygenase-2 (COX-2), 12-lipoxygenase (12-LOX), and inducible nitric oxide synthase (iNOS) have a role in carcinogenesis of head and neck squamous cell carcinoma (HNSCC).