The increase of mean platelet volume in patients with Alzheimer disease

KOÇ E. R., Uzar E., Cirak Y., Parlak Demir Y., Ilhan A.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.44, sa.6, ss.1060-1066, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3906/sag-1212-5
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1060-1066
  • Anahtar Kelimeler: Alzheimer disease, dementia, cognitive decline, mean platelet volume, platelet activation, vascular risk factors, AMYLOID PRECURSOR PROTEIN, VASCULAR RISK, ACTIVATION, MARKER, ASSOCIATION, PROGRESSION, DIAGNOSIS, AD
  • Gazi Üniversitesi Adresli: Evet

Özet

Background/aim: Vascular risk factors play an important role in the progression of Alzheimer disease (AD). Mean platelet volume (MPV) is a determinant of platelet functionality and increased MPV is associated with an increased risk of vascular inflammation. Here we aimed to examine whether MPV could be used as a marker of vascular damage in AD and to discuss the relation between MPV and other vascular risk factors.