The effect of intracerebroventricular amyloid beta 1-42 application on cognitive functions in aged rats supplemented with taurine and the change of peroxisomal proteins in this process


Karakelle N. A. , DİNCER S., YAR SAĞLAM A. S.

BRAIN RESEARCH BULLETIN, vol.172, pp.89-97, 2021 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 172
  • Publication Date: 2021
  • Doi Number: 10.1016/j.brainresbull.2021.04.011
  • Journal Name: BRAIN RESEARCH BULLETIN
  • Journal Indexes: Science Citation Index Expanded, Scopus, Academic Search Premier, Animal Behavior Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Psycinfo, Veterinary Science Database
  • Page Numbers: pp.89-97
  • Keywords: Oxidative stress, Peroxisome, Cognitive function, Taurine, Alzheimer&apos, s disease, OXIDATIVE STRESS, MITOCHONDRIAL DYSFUNCTION, LIPID-PEROXIDATION, ALZHEIMERS-DISEASE, MOUSE MODEL, MEMORY, INJECTION, PROTECTS, PROGRESS, ANXIETY

Abstract

Objective: The aim of our study is to investigate the change of peroxisomal proteins in the neurodegenerative and oxidative process caused by the neurotoxicity of A beta 1-42 in aged rats supplemented with taurine and to show the possible positive effects of taurine in this process.