Assessment of cytogenetic aberrations and comet assay in colorectal adenocarcinomas

Baltaci V., Sardas S., Aytac B., Cakar S., Karakaya A.

TUMORI, vol.89, no.3, pp.305-310, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 89 Issue: 3
  • Publication Date: 2003
  • Doi Number: 10.1177/030089160308900314
  • Journal Name: TUMORI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.305-310
  • Gazi University Affiliated: No

Abstract

Aims, background and study design: Few studies have investigated the karyotypes of colorectal carcinomas with emphasis on the correlation between cytogenetic findings and clinicopathologic features. The aim of our study involving 20 colorectal adenocarcinomas was to determine their genomic alterations at the chromosomal level by correlating the cytogenetic findings with the extent of DNA damage and clinicopathologic parameters and to compare the results with those of healthy controls.