The Effect of Subcutaneous Platelet-Rich Plasma Injection on Viability of Auricular Cartilage Grafts

Bulam H., AYHAN M. S., Yilmaz G., Sezgin B., ŞİBAR S., TUNCER S., ...More

JOURNAL OF CRANIOFACIAL SURGERY, vol.26, no.5, pp.1495-1499, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1097/scs.0000000000001819
  • Journal Name: JOURNAL OF CRANIOFACIAL SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1495-1499
  • Keywords: Cartilage grafts, cartilage viability, platelet-rich, plasma, HYALURONIC-ACID, GROWTH-FACTORS, RECONSTRUCTION, CHONDROCYTES, RHINOPLASTY, CELLS, PROLIFERATION, AUGMENTATION, SURGICEL, CULTURES
  • Gazi University Affiliated: Yes

Abstract

Introduction: Although cartilage grafts are frequently used for structural integrity and volume restoration, one of the main concerns dealing with cartilage grafting is gradual volume loss and unpredictable viability rates of cartilage grafts. Platelet-rich plasma (PRP) is a well known platelet concentrate reported to enhance cartilage repair and stimulates chondrocyte proliferation and matrix biosynthesis. The purpose of the current study was to investigate the effect of subcutaneous PRP injection on improving the viability of cartilage grafts.