Effects of hydroxyethyl starch 130/0.4 on the kidney tissue of rats with ureteral obstruction


Creative Commons License

GÜNEŞ I., SÜNGÜ N., KILIÇARSLAN A., ŞIVGIN V., ALKAN M., KÜÇÜK A., ...Daha Fazla

DRUG DESIGN DEVELOPMENT AND THERAPY, cilt.12, ss.3061-3070, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2147/dddt.s165695
  • Dergi Adı: DRUG DESIGN DEVELOPMENT AND THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3061-3070
  • Anahtar Kelimeler: unilateral ureteral obstruction, hydroxyethyl starch solution 130/0.4, caspase 3, caspase 8, malondialdehyde, nitric oxide, OXIDATIVE STRESS, NITRIC-OXIDE, LIPID-PEROXIDATION, SEVERE SEPSIS, RENAL DAMAGE, APOPTOSIS, INJURY, FIBROSIS, SURGERY, BYPASS
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: This study was conducted since the effects of colloid solutions on the renal system remain controversial and need to be adequately studied in animals. We aimed to evaluate the effects of hydroxyethyl starch (Voluven) on the kidney tissue of rats with late renal failure due to ureteral obstruction.