Maternal High Folic Acid Supplement and Relationship with Glucose Intolerance and Insulin Resistance in Offspring

Karaçil Ermumcu M. Ş. , Acar Tek N.

European Congress on Obesity (ECO2018), Vienna, Austria, 23 - 25 May 2018, pp.292

  • Publication Type: Conference Paper / Summary Text
  • City: Vienna
  • Country: Austria
  • Page Numbers: pp.292


Introduction: Folic acid is known as vitamin folate, is a form of synthetically produced water soluble vitamin found in fortified food and supplements. Humans are not able to synthesize folate de novo and, therefore, the daily requirements of folate are met with consumption of food rich in this vitamin and supplements. Biologically active folic acid is essential in meeting the requirements of the function of the human body. Folic acid is used to synthesize, repair and methylate deoxyribonucleic acid (DNA) therefore it is especially important in pregnancy and childhood for continuous cell division and growth. Folate deficiency can cause many health problems such as macrocytic anemia, weakness and confusion, memory deficits, shortness of breath, peripheral neuropathy, pregnancy complications, depression, hyperhomocysteinemia and cancer. Methods: This review aims to evaluate maternal high folic acid supplement and relationship with glucose ıntolerance and ınsulin resistance in offspring Results: Especially folic acid have preventive effect in pregnancy for neural tube and birth defects. Folic acid supplement recommendations in preconception and during pregnancy have been well established many