European Congress on Obesity (ECO2018), Vienna, Avusturya, 23 - 25 Mayıs 2018, ss.292
Introduction: Folic acid is known as vitamin folate, is a form of synthetically produced water soluble vitamin found in fortified food and supplements. Humans are not able to synthesize folate de novo and, therefore,
the daily requirements of folate are met with consumption of food rich in
this vitamin and supplements. Biologically active folic acid is essential in
meeting the requirements of the function of the human body. Folic acid
is used to synthesize, repair and methylate deoxyribonucleic acid (DNA)
therefore it is especially important in pregnancy and childhood for continuous cell division and growth. Folate deficiency can cause many health
problems such as macrocytic anemia, weakness and confusion, memory
deficits, shortness of breath, peripheral neuropathy, pregnancy complications, depression, hyperhomocysteinemia and cancer.
Methods: This review aims to evaluate maternal high folic acid supplement and relationship with glucose ıntolerance and ınsulin resistance in
offspring
Results: Especially folic acid have preventive effect in pregnancy for neural tube and birth defects. Folic acid supplement recommendations in
preconception and during pregnancy have been well established many