Clear Cell Adenocarcinoma of the Uterine Cervix: A Case Report and Review of the Literature

Baykara M., Benekli M., ERDEM O. A. , Taskiran C., Demirci U., Vargol E., ...More

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, vol.36, no.2, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.1097/mph.0b013e318290cb1b
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: uterine cervical tumors, diethylstilbestrol, clear cell cervix adenocarcinoma, CENTRAL NETHERLANDS REGISTRY, DIETHYLSTILBESTROL EXPOSURE, PROTEIN EXPRESSION, IN-UTERO, VAGINA, CARCINOMA, P53, PROGNOSIS, UPDATE
  • Gazi University Affiliated: Yes


We report an extremely rare case of a patient with clear cell carcinoma of the cervix who had no history of in utero diethylstilbestrol (DES) exposure. Although clear cell adenocarcinoma is an uncommon tumor, it must be considered in the differential diagnosis in young women and children who have cervico-vaginal lesions even without in utero DES exposure history. We present the case of 2 girls, a 14-year-old and a 16-year-old, who were admitted to hospital because of intermittent vaginal bleeding and the presence of a cervical mass diagnosed as clear cell cervix carcinoma. Neither of them had a history of exposure to DES.