Having some properties like low density, high temperature resistance, corrosion resistance and excellent biocompatibility, has made titanium and its alloys to be used in many industrial and biomedical applications. As a new production process, Powder Injection Molding (PIM) refers to a combination of powder metallurgy and plastic injection molding technologies. PIM method offers several unique advantages in mass production of small and complex-shaped parts. In this study, the PIM optimal parameters of molding and sintering stages, for fabricating of Ti-6Al-4V alloy has been determined. To realize the molding and sintering parameters, Taguchi method of experimental design has been applied. As a result, Ti-6Al-4V feedstock studies exhibited flow rate of 20 cm3/s, injection pressure of 1100 bar, holding pressure of 60%, injection temperature of 140 degrees C, sintering temperature of 1250 degrees C, sintering dwell time of 1 hour, sintering heating rate of 1 degrees C/min, gas flow rate of 10 lit/min, as optimum parameters.