No association between serum levels of insulin-like growth factor-I, vascular endothelial growth factor, prolactin and clinicopathological characteristics of breast carcinoma after surgery


Sancak B., Coskun U., Gunel N., Onuk E., Cihan A., Karamercan A., ...More

INTERNAL MEDICINE JOURNAL, vol.34, no.6, pp.310-315, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 6
  • Publication Date: 2004
  • Doi Number: 10.1111/j.1444-0903.2004.00591.x
  • Title of Journal : INTERNAL MEDICINE JOURNAL
  • Page Numbers: pp.310-315

Abstract

Background: Angiogenesis is essential for tumour growth and metastasis. Vascular endothelial growth factor (VEGF) has been suggested as the major angio-genic factor in breast carcinoma. Both insulin-like growth factor-I (IGF-I) and prolactin are involved in the progression of breast cancer at least partly by stimulating angiogenesis.