In Vitro Activity of Plazomicin Against Carbapenem Resistant Klebsiella pneumoniae Strains

Demirbas Z., ÖZGER H. S., Suzuk-Yildiz S., Bakkaloglu Z., DİZBAY M.

CLINICAL LABORATORY, vol.68, no.6, pp.1245-1250, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 68 Issue: 6
  • Publication Date: 2022
  • Doi Number: 10.7754/clin.lab.2021.210936
  • Journal Name: CLINICAL LABORATORY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.1245-1250
  • Keywords: plazomicin, carbapenem resistant K. pneumoniae, aminoglycoside modifying enzyme, aminoglycoside resistance, 16S ribosomal methylase, AMINOGLYCOSIDE-MODIFYING ENZYMES, ENTEROBACTERIACEAE, GENTAMICIN, TOBRAMYCIN
  • Gazi University Affiliated: Yes

Abstract

Background: In our study, we evaluated the in vitro activities of plazomicin, amikacin, gentamicin, and tobramycin among fifty carbapenem resistant Klebsiella pneumoniae (CR-Kp) isolates. Aminoglycoside resistance genes in selected CR-Kp strains were also examined.