EFFECT OF ALLOPURINOL ON MYOCARDIAL RECOVERY DURING REPERFUSION

SONCUL, H; GOKGOZ, L; KALAYCIOGLU, S; SINCI, V; KAPTANOGLU, M; ERSOZ, A

doi:10.3109/00365519309092526

EFFECT OF ALLOPURINOL ON MYOCARDIAL RECOVERY DURING REPERFUSION

Atıf İçin Kopyala

SONCUL H., GOKGOZ L., KALAYCIOGLU S., SINCI V., KAPTANOGLU M., ERSOZ A.

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, cilt.53, sa.1, ss.11-15, 1993 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 53 Sayı: 1
Basım Tarihi: 1993
Doi Numarası: 10.3109/00365519309092526
Dergi Adı: SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.11-15
Gazi Üniversitesi Adresli: Hayır

Özet

A comparative study on isolated guinea pig hearts was carried out to determine the effect of allopurinol added to reperfusion solution on myocardial recovery after global ischaemia. After 20 min of normothermic ischaemia two groups of solutions (1-Krebs Solution 2-Krebs Solution+Allopurinol 1 mmol l-1) were used for reperfusion (10 animals in each group). Post-ischaemic myocardial functions (ventricular contractile force and heart work) and enzyme activities (CK-MB, LD) were compared with their preischemic values.