Transient high altitude neurological dysfunction: An origin in the temporoparietal cortex

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Firth P., Bolay H. B.

HIGH ALTITUDE MEDICINE & BIOLOGY, vol.5, no.1, pp.71-75, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.1089/152702904322963708
  • Journal Name: HIGH ALTITUDE MEDICINE & BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.71-75
  • Keywords: hallucination, high altitude, high altitude cerebral edema, high altitude pulmonary edema, hypoxia, migraine, seizure, EXPERIENCES, PERCEPTION, PARIETAL, BRAIN
  • Gazi University Affiliated: Yes

Abstract

Firth, Paul G., Hayrunnisa Bolay. Transient high altitude neurological dysfunction: An origin in the temporoparietal cortex. High Alt. Med. Biol. 5:71-75, 2004.-This case report describes three separate episodes of isolated ataxia, hallucinations of being accompanied by another person, and bilateral dressing apraxia occurring in a single individual without prior warning signs. These symptoms are attributable to disruption of vestibular processing in the temporoparietal cortex or associated limbic structures. Neurological dysfunction at high altitude is usually ascribed to high altitude cerebral edema or acute mountain sickness. However, transient neurological symptoms occur abruptly at more extreme altitudes, often following vigorous exertion, without overt altitude-induced prodromes. These symptoms may be caused by intense neuronal discharge or neuronal synchronization as a feature of epileptic discharges or cortical spreading depression. Transient high altitude neurological dysfunction should be recognized as a separate complication of extreme altitude, distinct from high altitude cerebral edema.