Current Research in Dental Sciences, cilt.33, sa.4, ss.219-225, 2023 (Scopus)
Objective: The current clinical randomized study’s primary purpose was to investigate the antimicrobial efficiency of gaseous ozone on primary teeth root canals. Methods: The included teeth were randomly divided into three groups, and in each group, the root canal therapies of 12 primary teeth were done. In group 1, 2.5% sodium hypochlorite was applied as an irrigation agent. In group 2, 0.9% sterile saline solution was combined with 80 seconds OzonyTronX® application. In group 3, 2.5% sodium hypochlorite was applied as an intracanal medicament in combination with 80 seconds OzonyTronX®. Microbial analyses assessed the colo-nization of Candida albicans and Enterococcus faecalis before and after the procedure. Results: Thirty-six primary molars of 36 completely healthy patients (aged 5-10) were included in the study. The results revealed that the percentage decrease in the number of C. albicans was higher in group 3 (99.3%). This decrease was statistically higher than group 1 (96.1%) and group 2 (94.2%). Group 1 showed better results in eliminating the viable C. albicans versus group 2 (P = .033). The decrease in the number of E. faecalis was higher in group 3 (99.4%) compared to group 1 (99.1%) and group 2 (98.7%) (P = .006). Although the percentage of the unviable microor-ganisms was higher in group 1, there was no statistical difference versus group 2 (P > .05). Conclusion: Using gaseous ozone alone or in combination with sodium hypochlorite may enhance the success of the antimicrobial stage of primary root canal therapies. It could be an alternative to toxic chemical agents such as highly concentrated sodium hypochlorite.