Can the prognosis be predicted according to the localization of cerebellar ischemic lesions?


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ALTIPARMAK T., Nazliel B., Batur Caglayan H., TOKGOZ N.

Türk Beyin Damar Hastalıkları Dergisi, cilt.29, sa.2, ss.59-67, 2023 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 2
  • Basım Tarihi: 2023
  • Doi Numarası: 10.5505/tbdhd.2023.27167
  • Dergi Adı: Türk Beyin Damar Hastalıkları Dergisi
  • Derginin Tarandığı İndeksler: Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.59-67
  • Gazi Üniversitesi Adresli: Evet

Özet

INTRODUCTION: Damage to different anatomical structures within the cerebellum can lead to a variety of clinical findings. Moreover, these structures have different potentials for recovery from injury. Our objective was to assess the 6th and 12th-month outcomes of cerebellar ischemic stroke patients based on the localization of cerebellar ischemic lesion. METHODS: Our study included 82 patients who were admitted due to isolated cerebellar ischemic stroke without the involvement of any other brain regions. We recorded outcomes and survival rates for these patients and conducted statistical analyses, including frequency, univariate, and correlation analyses. RESULTS: More than three-quarters of patients were aged 60 years or older, and the majority of patients were male (57%). Hypertension (68%) and diabetes mellitus (34%) are the most common comorbid conditions. Like previous studies, multiple ischemic lesions (52%) were observed more than single lesions. The patients with the left peduncular region lesions had significantly higher NIHSS and mRS scores at discharge, as well as at 6 and 12 months follow-up compare with other cerebellar ischemic lesion localizations. Additionally, the survival rates at 6 and 12 months were found to be lower for these patients (p<0.05). DISCUSSION AND CONCLUSION: The presence of a left cerebellar peduncular ischemic lesion upon admission was significantly correlated with higher morbidity and mortality rates at discharge, as well as during the 6-12 month follow-up periods. Our results endorse the concept of the left cerebellar peduncles (superior, medial and inferior) causing permanent ambulation problems with poor outcomes in cerebellar lesions.