Consequences of hypoxia-reoxygenation phenomena in patients with obstructive sleep apnea syndrome


ULUKAVAK ÇİFTÇİ T. , KÖKTÜRK O. , Demirtas S., GÜLBAHAR Ö. , BUKAN N.

ANNALS OF SAUDI MEDICINE, cilt.31, sa.1, ss.14-18, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Konu: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.4103/0256-4947.75772
  • Dergi Adı: ANNALS OF SAUDI MEDICINE
  • Sayfa Sayıları: ss.14-18

Özet

BACKGROUND AND OBJECTIVES: Obstructive sleep apnea syndrome (OSAS) is a common disorder characterized by numerous episodes of absence of respiratory flow during sleep, which can be followed by a decrease in SaO(2), which is rapidly normalized when ventilation resumes. We hypothesize that this hypoxia-reoxygenation phenomena may affect the generation of vascular endothelial growth factor (VEGF), erythropoietin (EPO), endothelin-1 (ENDO-1), and inducible nitric oxide synthase (iNOS).