Consequences of hypoxia-reoxygenation phenomena in patients with obstructive sleep apnea syndrome
ANNALS OF SAUDI MEDICINE, cilt.31, sa.1, ss.14-18, 2011 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 1
- Basım Tarihi: 2011
- Doi Numarası: 10.4103/0256-4947.75772
- Dergi Adı: ANNALS OF SAUDI MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.14-18
- Gazi Üniversitesi Adresli: Evet
Özet
BACKGROUND AND OBJECTIVES: Obstructive sleep apnea syndrome (OSAS) is a common disorder characterized by numerous episodes of absence of respiratory flow during sleep, which can be followed by a decrease in SaO(2), which is rapidly normalized when ventilation resumes. We hypothesize that this hypoxia-reoxygenation phenomena may affect the generation of vascular endothelial growth factor (VEGF), erythropoietin (EPO), endothelin-1 (ENDO-1), and inducible nitric oxide synthase (iNOS).