Effects of alprostadil and iloprost on renal, lung, and skeletal muscle injury following hindlimb ischemia-reperfusion injury in rats


ERER D., ÖZER A., Demirtas H., IŞIK GÖNÜL İ., KARA H., Arpaci H., ...More

DRUG DESIGN DEVELOPMENT AND THERAPY, vol.10, pp.2651-2658, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10
  • Publication Date: 2016
  • Doi Number: 10.2147/dddt.s110529
  • Journal Name: DRUG DESIGN DEVELOPMENT AND THERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2651-2658
  • Keywords: alprostadil, iloprost, ischemia reperfusion injury, rat, renal, lung, skeletal muscle, PHENOMENON SECONDARY, RAYNAUDS-PHENOMENON, SYSTEMIC-SCLEROSIS, ADHESION, ISCHEMIA/REPERFUSION, TRANSPLANTATION, METABOLISM, INFUSION, KIDNEY, ACID
  • Gazi University Affiliated: Yes

Abstract

Objectives: To evaluate the effects of alprostadil (prostaglandin [PGE1] analog) and iloprost (prostacyclin [PGI2] analog) on renal, lung, and skeletal muscle tissues after ischemia reperfusion (I/R) injury in an experimental rat model.