Hypoxia-related molecules HIF-1α, CA9, and osteopontin : predictors of survival in patients with high-grade glioma.

Erpolat Ö. P., Gocun P. U., Akmansu M., Ozgun G., Akyol G.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], vol.189, no.2, pp.147-54, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 189 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1007/s00066-012-0262-5
  • Journal Name: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.147-54
  • Keywords: High-grade glioma, Hypoxia, Osteopontin, Survival, Prognostic factors, INDUCIBLE FACTOR-1, TUMOR HYPOXIA, EXPRESSION, ANGIOGENESIS, GLIOBLASTOMA, BRAIN, OVEREXPRESSION, IDENTIFICATION, BIOMARKERS, PROGNOSIS
  • Gazi University Affiliated: Yes

Abstract

A high expression of hypoxia-inducible factor-1 alpha (HIF)-1 alpha, carbonic anhydrase 9 (CA9), aontin appears to be a strong prognostic indicator in many malignancies; however, their role is unclear in high-grade gliomas.