Effects of Picroside II on Myocardial Ischemia-Reperfusion Injury in Streptozotocin-Induced Diabetic Rats

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Polat Y., DURSUN A. D., KÜÇÜK A., ÖZER A., ERER D., ARSLAN M.

GAZI MEDICAL JOURNAL, cilt.28, sa.1, ss.27-30, 2017 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.12996/gmj.2017.07
  • Dergi Adı: GAZI MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.27-30
  • Anahtar Kelimeler: Ischemia-reperfusion, total oxidant status, total antioxidant status, picroside II, myocardial tissue, rat, TOLL-LIKE-RECEPTORS, LIPID-PEROXIDATION, PICRORHIZA-KURROA, RENAL INJURY, T-CELLS, ILOPROST, MODULATION, EXPRESSION, OXYGEN, LIVER
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Diabates mellitus, is a chronic metabolic disorder accompanied by an increase in oxidative stress. Ischemia-reperfusion injury is a cascade of events initiated by tissue ischemia. The cellular damage produced by reperfusion leads to an active inflammatory response. This study was performed to investigate the effect of picroside II on myocardial ischemiareperfusion injury in rats with streptozotocin-induced diabetes.