Kounis syndrome secondary to amoxicillin/clavulanic acid use

Tavil Y., Turfan M., TÜRKOĞLU S., ABACI A.

INTERNATIONAL JOURNAL OF CARDIOLOGY, cilt.124, sa.1, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Kısa Makale
  • Cilt numarası: 124 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.ijcard.2006.11.165
  • Dergi Adı: INTERNATIONAL JOURNAL OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: allergic myocardial angina, amoxicillin/clavulanic acid, Kounis syndrome, ALLERGIC MYOCARDIAL-INFARCTION, ANGINA
  • Gazi Üniversitesi Adresli: Evet

Özet

Myocardial injury and acute coronary syndrome have been rarely associated with amoxicillin/clavulanic acid intake. The responsible pathogenetic mechanism is described by an amplified mast cell degranulation inducing coronary artery spasm and/or acute myocardial infarction in susceptible individuals which is called Kounis syndrome. We report here a case of Kounis syndrome presented with acute coronary syndrome due to amoxicillin/clavulanic acid use. All other etiologies, including ischemic reinfarction were appropriately ruled out. (C) 2007 Elsevier Ireland Ltd. All rights reserved.