Visual and Quantitative Analysis of <SUP>123</SUP>I-Ioflupane SPECT Reveals Asymmetric Neuronal Degeneration in Fahr's Disease
CLINICAL NUCLEAR MEDICINE, cilt.51, sa.7, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Editöre Mektup
- Cilt numarası: 51 Sayı: 7
- Basım Tarihi: 2026
- Doi Numarası: 10.1097/rlu.0000000000006243
- Dergi Adı: CLINICAL NUCLEAR MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Gazi Üniversitesi Adresli: Evet
Özet
Fahr's disease is a rare disorder characterized by bilateral and symmetric calcifications in brain structures, including the basal ganglia, cerebellum, thalamus, and cerebral white matter. The findings of I-123-Ioflupane SPECT in Fahr's disease have only been reported in a limited number of case reports. We present the case of a 64-year-old woman with Fahr's disease who had reduced uptake in the striatum on both visual and quantitative assessment of I-123-Ioflupane SPECT images. The striatal involvement was asymmetric, despite the presence of substantially symmetric calcifications on CT and MRI.