Osteogenesis Imperfecta and Extra-/Intradural Hematomas: A Case Report and Review of the Literature

Creative Commons License

Yakar F., ÇELTİKÇİ E., Ozgural O., Eroglu U., ÇAĞLAR Y. Ş.

JOURNAL OF PEDIATRIC GENETICS, vol.7, no.4, pp.185-190, 2018 (ESCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 7 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1055/s-0038-1660826
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.185-190
  • Gazi University Affiliated: Yes


Osteogenesis imperfecta, also named as brittle bone disease, is characterized by fragile bones and short stature caused by mutations in the collagen gene. Subdural and intraparenchymal hematomas are defined and associated with trauma, vascular causes, and systemic bleeding diathesis. Skull fragility may lead to epidural hematoma, which is a life-threatening situation. Vascular fragility and intrinsic platelet defects are the causes of bleeding in patients with osteogenesis imperfecta, which is a major management challenge for neurosurgeons. Here, we reported on a 5-year-old boy with osteogenesis imperfecta with epidural hematoma and skull fracture following a trivial trauma, and made a literature review of 28 cases with extra-/intradural hematoma.