The Effects of Minocycline on the Hippocampus in Lithium- Pilocarpine Induced Status Epilepticus in Rat: Relations with Microglial/Astrocytic Activation and Serum S100B Level.


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Bulduk E. B. , KURT G. , BARUN S. , Aydemir O., Kiziltas M., Oktem M. , ...More

Turkish neurosurgery, vol.29, no.1, pp.95-105, 2019 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.5137/1019-5149.jtn.22744-18.1
  • Title of Journal : Turkish neurosurgery
  • Page Numbers: pp.95-105

Abstract

AIM: To investigate possible correlations between serum S100B levels and microglial/astrocytic activation in status epilepticus (SE) in lithium-pilocarpine-exposed rat hippocampi and whether serum S100B levels linearly reflect neuroinflammation. Additionally, to assess the effects of minocycline (M), an inhibitor of neuroinflammation.