Gray hair and acrodermatitis enteropathica-like dermatitis: an unexpected presentation of cystic fibrosis


DALGIÇ B. , EĞRİTAŞ GÜRKAN Ö.

EUROPEAN JOURNAL OF PEDIATRICS, vol.170, no.10, pp.1305-1308, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 170 Issue: 10
  • Publication Date: 2011
  • Doi Number: 10.1007/s00431-011-1447-0
  • Title of Journal : EUROPEAN JOURNAL OF PEDIATRICS
  • Page Numbers: pp.1305-1308

Abstract

Presentation of cystic fibrosis (CF) with an acrodermatitis enteropathica-like skin rash, anemia, and hypoproteinemia without pulmonary disease is rarely reported before. We describe an 11-month-old boy with rash and edema as the presenting signs of cystic fibrosis. The interesting additional finding in our patient was the graying hair after 3 months of age. A reversal of the gray hair was observed by pancreatic enzyme replacement therapy. In conclusion, acrodermatitis-like eruption and hypoproteinemia can be a presenting sign of CF. Graying hair has not been noticed so far as a sign of CF in these patients.