Purpose: To evaluate and compare the presence and extent of ischemic findings in brain magnetic resonance images (MRI) of patients with normal tension glaucoma (NTG), primary open-angle glaucoma (POAG), and control subjects. Method: Seventeen patients with NTG underwent MRI. Cortical atrophy and cerebral infarcts were graded in a masked fashion by a neuroradiologist and findings were compared with age- and sex-matched POAG patients and controls. Results: In terms of CNS ischemia, patients with NTG showed more pathological findings compared to POAG and controls. The latter two were found to be statistically similar. Also, these findings were not related to age.