Evaluation of the Effects of Recurrent Dexmedetomidine on Cognitive Functions and Brain Tissue in Streptozotocin-Induced Rats with Alzheimer's Disease

ARSLAN M., KÜÇÜK A., Kiran M. M., KÖKSAL Z., KURTİPEK Ö., KAVUTÇU M.

GAZI MEDICAL JOURNAL, cilt.33, sa.1, ss.5-9, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.12996/gmj.2022.02
  • Dergi Adı: GAZI MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier
  • Sayfa Sayıları: ss.5-9
  • Anahtar Kelimeler: Alzheimer, dexmedetomidine, Radial Arm Maze Test, rat, GFAP, TBARS, Catalase, GENERAL-ANESTHESIA, DYSFUNCTION, EXPOSURE, SURGERY, PHOSPHORYLATION, OLIGOMERIZATION, ISOFLURANE, RISK
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study was to evaluate the effects of recurrent dexmedetomidine on cognitive functions and brain histopathology in the elderly rat model which has Alzheimer disease created with streptozocin (STZ).