Circulating Kisspeptin and Klotho Levels in Women with Hyperprolactinemia
TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, cilt.26, sa.3, ss.115-119, 2022 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 26 Sayı: 3
- Basım Tarihi: 2022
- Doi Numarası: 10.5152/tjem.2022.22068
- Dergi Adı: TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.115-119
- Anahtar Kelimeler: Hyperprolactinemia, kisspeptin, klotho, neurokinin B, pituitary, HORMONE-SECRETION, ARCUATE NUCLEUS, PROLACTIN, NEURONS, EXPRESSION, RELEASE, OBESITY, KISS-1
- Gazi Üniversitesi Adresli: Evet
Özet
Objective: Kisspeptin is a neuropeptide that acts mainly on gonadotropin-releasing hormone in the hypothalamus with neurokinin B and dynorphin. Also, its peripheral effects have gained importance in recent years. Klotho is an anti-aging transmembrane glycoprotein with growth hormone and insulin-like growth factor-1-related effects. Both kisspeptin and klotho seem to interact with prolactin in the hypothalamic-pituitary region. In this study, we aimed to investigate the relationship between hyperprolactinemia and circulating kisspeptin and klotho levels.