Circulating Kisspeptin and Klotho Levels in Women with Hyperprolactinemia

Arslan I. E., Ozturk B. O., Bolayir B., YALÇIN M. M., YETKİN İ., AKTÜRK M. Y.

TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, cilt.26, sa.3, ss.115-119, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5152/tjem.2022.22068
  • Dergi Adı: TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.115-119
  • Anahtar Kelimeler: Hyperprolactinemia, kisspeptin, klotho, neurokinin B, pituitary, HORMONE-SECRETION, ARCUATE NUCLEUS, PROLACTIN, NEURONS, EXPRESSION, RELEASE, OBESITY, KISS-1
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: Kisspeptin is a neuropeptide that acts mainly on gonadotropin-releasing hormone in the hypothalamus with neurokinin B and dynorphin. Also, its peripheral effects have gained importance in recent years. Klotho is an anti-aging transmembrane glycoprotein with growth hormone and insulin-like growth factor-1-related effects. Both kisspeptin and klotho seem to interact with prolactin in the hypothalamic-pituitary region. In this study, we aimed to investigate the relationship between hyperprolactinemia and circulating kisspeptin and klotho levels.