Role of serum toll-like receptors 2 and 4 in non-alcoholic steatohepatitis and liver fibrosis


Cengiz M., Ozenirler S., Elbeg S.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol.30, no.7, pp.1190-1196, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 7
  • Publication Date: 2015
  • Doi Number: 10.1111/jgh.12924
  • Title of Journal : JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
  • Page Numbers: pp.1190-1196

Abstract

Background and AimNon-alcoholic fatty liver disease is a common cause of chronic liver disease, including non-alcoholic steatohepatitis (NASH). Our aim was to investigate whether serum toll-like receptors 2 and 4 (TLR2 and TLR4) levels are correlated with NASH and able to predict liver fibrosis, as well as to compare these markers with other non-invasive fibrosis scores (aspartate aminotransferase [AST] to alanine aminotransferase ratio, AST to platelet ratio index, fibrosis index, fibrosis 4, and fibrosis cirrhosis index).