Oxidized low-density lipoprotein levels and carotid intima-media thickness as markers of early atherosclerosis in prepubertal obese children

OKUR İ., TÜMER L., EZGÜ F. S., Yesilkaya E., Aral A., ÖZHAN OKTAR S., ...Daha Fazla

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.26, ss.657-662, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1515/jpem-2012-0374
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.657-662
  • Anahtar Kelimeler: carotid IMT, oxidized LDL, prepubertal obesity, CARDIOVASCULAR RISK-FACTORS, AMBULATORY BLOOD-PRESSURE, ENDOTHELIAL DYSFUNCTION, INSULIN-RESISTANCE, CHILDHOOD OBESITY, FAMILIAL HYPERCHOLESTEROLEMIA, HEALTHY POPULATION, METABOLIC SYNDROME, ADOLESCENT GIRLS, TURKISH CHILDREN
  • Gazi Üniversitesi Adresli: Evet

Özet

Objectives: Children with obesity have a high cardiovascular risk and an impaired oxidant-antioxidant status, which may lead to endothelial dysfunction and increased carotid intima media thickness (IMT) even in childhood. The aim of this study was to investigate the circulating oxidized low-density lipoprotein (LDL) concentrations and the IMT of carotid arteries in prepubertal obese children, and also to search for its possible association with carotid atherosclerosis.