Effect of Oral TGF-A Formulations on ASA Induced Duodenal Ulcer and The Role of Lipid Peroxidation in The Healing Process

Özer, ÇİĞDEM; Gonul, Bilge; Celebi, Nevin; Yetkin, Gulay; Elmas, ÇİĞDEM; Erdogan, Deniz

doi:10.5505/tjb.2012.53215

Effect of Oral TGF-A Formulations on ASA Induced Duodenal Ulcer and The Role of Lipid Peroxidation in The Healing Process

Özer Ç., Gonul B., Celebi N., Yetkin G., Elmas Ç., Erdogan D.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.37, ss.294-302, 2012 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 37
Basım Tarihi: 2012
Doi Numarası: 10.5505/tjb.2012.53215
Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.294-302
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Gazi Üniversitesi Adresli: Evet

Özet

Objective: This study was designed to investigate the effects of aqueous or Microemulsion solution containing Transforming Growth factors-alpha (TGF-a) and/or administration of aprotinin on healing rate of duodenal ulcer induced by acetylsalicylic acid, and to examine the relationships between oxidative processes and TGF-a formulation during duodenal ulcer healing by measuring malondialdehyde, glutathione and total nitric oxide levels.