Effect of Oral TGF-A Formulations on ASA Induced Duodenal Ulcer and The Role of Lipid Peroxidation in The Healing Process


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Özer Ç., Gonul B., Celebi N., Yetkin G., Elmas Ç., Erdogan D.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.37, ss.294-302, 2012 (SCI-Expanded) identifier identifier

Özet

Objective: This study was designed to investigate the effects of aqueous or Microemulsion solution containing Transforming Growth factors-alpha (TGF-a) and/or administration of aprotinin on healing rate of duodenal ulcer induced by acetylsalicylic acid, and to examine the relationships between oxidative processes and TGF-a formulation during duodenal ulcer healing by measuring malondialdehyde, glutathione and total nitric oxide levels.