Akademik Veri Yönetim Sistemi
Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.48, sa.1, ss.1-15, 2023 (Scopus)
Objective: Rheumatoid arthritis is an autoimmune disease that can cause damage to bones, cartilage, tendons and ligaments. Its treatment includes non-specific, systemic administration of glucocorticoids, DMARDs and biologics to relieve symptoms. In traditional treatment approaches, drugs need to be administered at frequent intervals and in high doses, which causes side effects that reduce the quality of life of patients. It is possible to develop nano-sized drug delivery systems for the treatment of rheumatoid arthritis and deliver them to the areas of inflammation, thus reducing the dose of drugs and minimizing their systemic side effects. Result and Discussion: As shown in many studies, the use of various drug delivery systems as an alternative to traditional treatment methods in the treatment of rheumatoid arthritis has shown very positive results in terms of prevention and alleviation of the symptoms of the disease. It is thought that there will be promising developments in the treatment of rheumatoid arthritis in the coming years utilizing of various targeting approaches as in cancer treatment.