Effects of topical vitamin E on corneal superoxide dismutase, glutathione peroxidase activities and polymorphonuclear leucocyte infiltration after photorefractive keratectomy

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Bilgihan A., Bilgihan K., Yis O., Sezer C., Akyol G., Hasanreisoglu B.

ACTA OPHTHALMOLOGICA SCANDINAVICA, vol.81, no.2, pp.177-180, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 81 Issue: 2
  • Publication Date: 2003
  • Doi Number: 10.1034/j.1600-0420.2003.00042.x
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.177-180
  • Keywords: photorefractive keratectomy, vitamin E, superoxide dismutase, glutathione peroxidase, polymorphonuclear cell infiltration, SURGERY, TISSUE, ACID
  • Gazi University Affiliated: Yes


Purpose: Photorefractive keratectomy (PRK) induces free radical formation and polymorphonuclear (PMN) cell infiltration in the cornea. Vitamin E is a free radical scavenger and protects the cells from reactive oxygen species. We investigated the effects of topical vitamin E on corneal PMN cell infiltration and corneal antioxidant enzyme activities after PRK.