Double aneuploidy in spontaneous miscarriages: Two case reports and review of the literature

Korucuoglu U., ERDEM M., Pala E., YİRMİBEŞ KARAOĞUZ M., ERDEM A., Biri A.

FETAL DIAGNOSIS AND THERAPY, cilt.24, sa.2, ss.106-110, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 24 Sayı: 2
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1159/000142138
  • Dergi Adı: FETAL DIAGNOSIS AND THERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.106-110
  • Gazi Üniversitesi Adresli: Evet

Özet

The occurrence of double aneuploidy is a relatively rare phenomenon. The clinical presentations are variable depending on the predominating aneuploidy or a combination effect of both. We report the cytogenetic data on products of conception from miscarriages over a period of 5 years. A total of 403 miscarriages were karyotyped and the tissues were villi in all cases. Of 403 cases, 54 cases with single aneuploidy and 2 cases of first-trimester miscarriages with double trisomies were found. These 2 cases with the karyotypes of 48, XXY,+15 and 48, XX,+ 5,+ 7 were cited for the first time in this study. Copyright (C) 2008 S. Karger AG, Basel.