A Case Report on Simultaneous Covid-19 and Rapidly Progressive Glomerulonephritis Management in a Patient with Granulomatosis Polyangiitis

Bas D., KÜÇÜK H.

GAZI MEDICAL JOURNAL, vol.32, no.4, pp.585-588, 2021 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.12996/gmj.2021.131
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier
  • Page Numbers: pp.585-588
  • Keywords: COVID-19, Granulomatous polyangiosis, immunosuppressive therapy, RPGN
  • Gazi University Affiliated: Yes


Granulomatous polyangiosis (GPA) is a systemic necrotizing granulomatous vasculitis effected the upper-lower airways and the kidney. Small and middle diameter arteries are involved, especially. It is the one of the ANCA associated vasculitis and its characteristic pathological finding is the formation of granulomas. Female and male are affected approximately equally and the average diagnosis is around 40-50 years old. The main symptoms are fever, weakness, sweating, weight loss, myalgia, arthralgia. Respiratory tract, lung, kidney, skin and peripheral nerve involvement are observed. Pulmonary-renal failure, infection and treatment side effects are causes of mortality.