Effects of dexamethasone and pheniramine hydrogen maleate on stress response in patients undergoing elective laparoscopic cholecystectomy


Karaman K., Bostanci E. B. , Aksoy E., Ulas M., Yigit T., Erdemli M. O. , ...More

AMERICAN JOURNAL OF SURGERY, vol.205, no.2, pp.213-219, 2013 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 205 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1016/j.amjsurg.2012.05.010
  • Journal Name: AMERICAN JOURNAL OF SURGERY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.213-219
  • Keywords: Dexamethasone, Pheniramine hydrogen maleate, Laparoscopic cholecystectomy, POSTOPERATIVE NAUSEA, PREOPERATIVE DEXAMETHASONE, HISTAMINE-RELEASE, H-1, PROPHYLAXIS, PREVENTION, TRIAL

Abstract

BACKGROUND: Laparoscopic cholecystectomy (LC) still leads to significant postoperative nausea and vomiting (PONV) and pain. Our aim was to evaluate the efficacy of dexamethasone or pheniramine hydrogen maleate, either alone or combined, in reducing the stress response and symptoms after LC.