Perioperative alendronate, risedronate, calcitonin and indomethacin treatment alters femoral stem fixation and periprosthetic bone mineral density in ovariectomized rats

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Cankaya D., Tabak Y., ÖZTÜRK A. M., Gunay M. C.

JOURNAL OF ORTHOPAEDIC SCIENCE, cilt.20, sa.4, ss.728-733, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s00776-015-0717-5
  • Dergi Adı: JOURNAL OF ORTHOPAEDIC SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.728-733
  • Gazi Üniversitesi Adresli: Evet

Özet

Many factors affect implant stability and periprosthetic bone mineral density (BMD) following total joint arthroplasty. We asked whether perioperative alendronate, risedronate, calcitonin and indomethacine administration altered (1) femoral stem shear strength and periprosthetic bone mineral density BMD in ovariectomized rats and (2) whether there were differences in the effect of these drugs.