Perioperative alendronate, risedronate, calcitonin and indomethacin treatment alters femoral stem fixation and periprosthetic bone mineral density in ovariectomized rats


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Cankaya D., Tabak Y., ÖZTÜRK A. M. , Gunay M. C.

JOURNAL OF ORTHOPAEDIC SCIENCE, cilt.20, sa.4, ss.728-733, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 20 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s00776-015-0717-5
  • Dergi Adı: JOURNAL OF ORTHOPAEDIC SCIENCE
  • Sayfa Sayıları: ss.728-733

Özet

Many factors affect implant stability and periprosthetic bone mineral density (BMD) following total joint arthroplasty. We asked whether perioperative alendronate, risedronate, calcitonin and indomethacine administration altered (1) femoral stem shear strength and periprosthetic bone mineral density BMD in ovariectomized rats and (2) whether there were differences in the effect of these drugs.