Perioperative alendronate, risedronate, calcitonin and indomethacin treatment alters femoral stem fixation and periprosthetic bone mineral density in ovariectomized rats

Cankaya, Deniz; Tabak, Yalcin; ÖZTÜRK, AKİF; Gunay, Muhammed

doi:10.1007/s00776-015-0717-5

Perioperative alendronate, risedronate, calcitonin and indomethacin treatment alters femoral stem fixation and periprosthetic bone mineral density in ovariectomized rats

Cankaya D., Tabak Y., ÖZTÜRK A. M., Gunay M. C.

JOURNAL OF ORTHOPAEDIC SCIENCE, cilt.20, sa.4, ss.728-733, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 4
Basım Tarihi: 2015
Doi Numarası: 10.1007/s00776-015-0717-5
Dergi Adı: JOURNAL OF ORTHOPAEDIC SCIENCE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.728-733
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Gazi Üniversitesi Adresli: Evet

Özet

Many factors affect implant stability and periprosthetic bone mineral density (BMD) following total joint arthroplasty. We asked whether perioperative alendronate, risedronate, calcitonin and indomethacine administration altered (1) femoral stem shear strength and periprosthetic bone mineral density BMD in ovariectomized rats and (2) whether there were differences in the effect of these drugs.