Vitamin D and Diabetes Mellitus

Iyidir O. T., EROĞLU ALTINOVA A.

TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, cilt.16, sa.4, ss.89-94, 2012 (ESCI) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 16 Sayı: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.4274/tjem.1968
  • Dergi Adı: TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.89-94
  • Anahtar Kelimeler: Vitamin D, diabetes mellitus, type 1, type 2, immune system, calcium, RECEPTOR GENE POLYMORPHISMS, COD-LIVER OIL, 25-HYDROXYVITAMIN D CONCENTRATIONS, BONE-MINERAL DENSITY, D-BINDING PROTEIN, INSULIN SENSITIVITY, D SUPPLEMENTATION, D DEFICIENCY, GLUCOSE-TOLERANCE, CALCIUM INTAKE
  • Gazi Üniversitesi Adresli: Evet

Özet

Recent epidemiological data have established a link between vitamin D deficiency and type 1 and type 2 diabetes mellitus (DM). Experimental evidence also supported the idea that vitamin D may play a role in the pathogenesis of DM. Additionally, it has been reported that vitamin D supplementation may decrease the risk of developing DM in long term period. The protective effects of vitamin D are mediated through the immune system and calcium metabolism. Vitamin D may also have a direct effect on pancreatic beta cells.