The expression of VLA integrins in the human tonsilla palatina

Karaoz E., Ilgaz C., Erdogan D., Dagdeviren A.

ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER, vol.179, no.2, pp.149-156, 1997 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 179 Issue: 2
  • Publication Date: 1997
  • Doi Number: 10.1016/s0940-9602(97)80092-1
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.149-156


The integrin receptors are a family of transmembrane glycoproteins comprising non-covalent heterodimers. They interact with a wide variety of ligands including extracellular matrix glycoproteins, complement and other cell, while their intracellular domains interact with the cytoskeleton. They participate in cell-matrix and cell-cell adhesion in many physiologically important processes including embryological development, hemostasis, thrombosis, wound healing, immune and nonimmune defense mechanisms, and in oncogenic transformation. This investigation was focused on the histological distribution of the Beta 1-integrins in the human tonsil using an indirect immunoperoxidase method.