Gelatinase B expression as a prognostic factor in patients with stage II/III rectal carcinoma treated by postoperative adjuvant therapy.

Unsal D., AKYÜREK N., ÜNER A., Erpolat P., Han U., AKMANSU M., ...Daha Fazla

American journal of clinical oncology, cilt.31, sa.1, ss.55-63, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1097/coc.0b013e318068b4e2
  • Dergi Adı: American journal of clinical oncology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.55-63
  • Anahtar Kelimeler: rectal cancer, radiotherapy, matrix metalloproteinase, gelatinase, prognostic factor, COLORECTAL-CANCER, TISSUE INHIBITOR, MATRIX METALLOPROTEINASES, MMP-2, MATRILYSIN, TIMP-2
  • Gazi Üniversitesi Adresli: Evet

Özet

Objective: The matrix-metalloproteinases (MMPs) are thought to be critically involved in tumor invasion and metastasis. This retrospective study was aimed both to examine the gelatinase expression status in patients with rectal cancer and to investigate their prognostic value on survival.