Relationship between Serum Adipocyte Fatty Acid-Binding Protein Levels and Systemic Inflammation in Hemodialysis Patients


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Korucu B. , Derici M. K. , Deger S. M. , Cokay A., Helvaci O., Elbeg S., ...Daha Fazla

TURKISH JOURNAL OF NEPHROLOGY, cilt.29, ss.115-121, 2020 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 29
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/turkjnephrol.2020.3686
  • Dergi Adı: TURKISH JOURNAL OF NEPHROLOGY
  • Sayfa Sayıları: ss.115-121

Özet

Objective: Adipocyte fatty acid-binding protein (A-FABP) is expressed in adipose tissue and macrophages. It regulates cholesterol trafficking and is involved in atherosclerosis formation. A-FABP levels are associated with cardiovascular diseases (CVDs) in patients with or without chronic kidney disease. In this study, we evaluated A-FABP levels in healthy controls and hemodialysis (HD) patients and compared the results with C-reactive protein (CRP) and interleukin-6 (IL-6) levels to determine their relationship with systemic inflammation.