Effects of dexmedetomidine on renal tissue after lower limb ischemia reperfusion injury in streptozotocin induced diabetic rats

Erbatur M. E., SEZEN Ş. C., Bayraktar A. C., ARSLAN M., KAVUTÇU M., AYDIN M. E.

LIBYAN JOURNAL OF MEDICINE, cilt.12, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/19932820.2017.1270021
  • Dergi Adı: LIBYAN JOURNAL OF MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Ischemia reperfusion, dexmedetomidine, renal, diabetes, TBARS, SOD, NOS, histopathology, ISCHEMIA/REPERFUSION INJURY, LUNG INJURY, INFUSION, REVERSAL, FAILURE, SURGERY, KIDNEY, DAMAGE
  • Gazi Üniversitesi Adresli: Evet

Özet

Aim: The aim of this study was to investigate whether dexmedetomidine - administered before ischemia - has protective effects against lower extremity ischemia reperfusion injury that induced by clamping and subsequent declamping of infra-renal abdominal aorta in streptozotocin-induced diabetic rats.