Nasal Immune Responses to Human Metapneumovirus


Leitich I. C. , Mogaka E.

TURKISH JOURNAL OF IMMUNOLOGY, vol.7, no.3, pp.125-131, 2019 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.25002/tji.2019.1173
  • Journal Name: TURKISH JOURNAL OF IMMUNOLOGY
  • Journal Indexes: Emerging Sources Citation Index, Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.125-131
  • Keywords: Human Metaapneumovirus (hMPV), ARI, nasal immune responses, interleukins, determinative, diagnostic, RESPIRATORY SYNCYTIAL VIRUS, CLINICAL-DISEASE, VIRAL LOAD, INFECTION, GLYCOPROTEIN, SEVERITY, CELL

Abstract

Introduction: Human metapneumovirus (hMPV) with tropism for the respiratory tract epithelium, causes 5-10% of all acute respiratory tract infections (ARI). Patients may be asymptomatic, or exhibit mild upper respiratory tract symptoms or severe bronchiolitis and pneumonia. Determinative diagnostic markers for infection are not well elucidated. This study on nasal immune responses to hMPV aims to understand the mucosal immune responses to hMPV and its implication in disease resolution and pathology.