Nasal Immune Responses to Human Metapneumovirus

Leitich I. C., Mogaka E.

TURKISH JOURNAL OF IMMUNOLOGY, cilt.7, sa.3, ss.125-131, 2019 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.25002/tji.2019.1173
  • Dergi Adı: TURKISH JOURNAL OF IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.125-131
  • Anahtar Kelimeler: Human Metaapneumovirus (hMPV), ARI, nasal immune responses, interleukins, determinative, diagnostic, RESPIRATORY SYNCYTIAL VIRUS, CLINICAL-DISEASE, VIRAL LOAD, INFECTION, GLYCOPROTEIN, SEVERITY, CELL
  • Gazi Üniversitesi Adresli: Evet

Özet

Introduction: Human metapneumovirus (hMPV) with tropism for the respiratory tract epithelium, causes 5-10% of all acute respiratory tract infections (ARI). Patients may be asymptomatic, or exhibit mild upper respiratory tract symptoms or severe bronchiolitis and pneumonia. Determinative diagnostic markers for infection are not well elucidated. This study on nasal immune responses to hMPV aims to understand the mucosal immune responses to hMPV and its implication in disease resolution and pathology.