Acute adrenal crisis mimicking familial Mediterranean fever attack in a renal transplant FMF patient with amyloid goiter


Emeksiz H., Bakkaloglu S., Camurdan O., Boyraz M., Soylemezoglu O., Hasanoglu E., ...More

RHEUMATOLOGY INTERNATIONAL, vol.30, no.12, pp.1647-1649, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 12
  • Publication Date: 2010
  • Doi Number: 10.1007/s00296-009-1115-0
  • Title of Journal : RHEUMATOLOGY INTERNATIONAL
  • Page Numbers: pp.1647-1649

Abstract

The most devastating complication of familial Mediterranean fever (FMF) is amyloidosis which is capable of resulting in chronic renal failure. Although amyloid deposits are frequent in adrenal glands based on the autopsies of FMF patients however; to our knowledge, symptomatic adrenal insufficiency has not been reported yet. We describe a 21-year-old-FMF amyloidosis case with a well-functioning allograft who presented to the emergency clinic with the complaints of abdominal pain, vomiting and diarrhea mimicking FMF attack. adrenocorticotrophic hormone stimulation test was performed due to resistant hyponatremia and disclosed Addison disease. In countries with a high prevalence of FMF, adrenal crisis should be borne in mind in long standing FMF patients.