Granulocytic sarcoma after stem cell transplantation in a child with biphenotypic leukemia


Kaya Z., KOÇAK Ü. , Albayrak M., Gursel T., AKYÜREK N. , ÖZHAN OKTAR S.

TURKISH JOURNAL OF HEMATOLOGY, vol.26, no.3, pp.151-153, 2009 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 3
  • Publication Date: 2009
  • Title of Journal : TURKISH JOURNAL OF HEMATOLOGY
  • Page Numbers: pp.151-153

Abstract

Granulocytic sarcoma is an extramedullary tumor composed of leukemic blasts. Isolated granulocytic sarcoma has rarely been reported in children with leukemia undergoing allogeneic stem cell transplantation. We report a case of isolated granulocytic sarcoma arising from the pleura in an 11-year-old girl who was previously treated for biphenotypic leukemia with allogeneic stem cell transplantation. Complete resolution of the tumor was achieved after two inductions with MRC 12 protocol; however, she died of sepsis during the neutropenic period. The unusual presentation, immunophenotypic differences at diagnosis and relapse, and the management options are discussed. (Turk J Hematol 2009; 26: 151-3)