Granulocytic sarcoma after stem cell transplantation in a child with biphenotypic leukemia

Kaya Z., KOÇAK Ü., Albayrak M., Gursel T., AKYÜREK N., ÖZHAN OKTAR S.

TURKISH JOURNAL OF HEMATOLOGY, cilt.26, sa.3, ss.151-153, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 3
  • Basım Tarihi: 2009
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.151-153
  • Gazi Üniversitesi Adresli: Evet

Özet

Granulocytic sarcoma is an extramedullary tumor composed of leukemic blasts. Isolated granulocytic sarcoma has rarely been reported in children with leukemia undergoing allogeneic stem cell transplantation. We report a case of isolated granulocytic sarcoma arising from the pleura in an 11-year-old girl who was previously treated for biphenotypic leukemia with allogeneic stem cell transplantation. Complete resolution of the tumor was achieved after two inductions with MRC 12 protocol; however, she died of sepsis during the neutropenic period. The unusual presentation, immunophenotypic differences at diagnosis and relapse, and the management options are discussed. (Turk J Hematol 2009; 26: 151-3)