An adolescent case of extensive Behcet's disease successfully treated with Infliximab

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Isiyel E., Bakkaloglu S. A. , Oguz D., Yenicesu I., Boyunaga O., Ozdemir Y., ...More

TURKISH JOURNAL OF PEDIATRICS, vol.61, no.4, pp.585-588, 2019 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.24953/turkjped.2019.04.016
  • Journal Indexes: Science Citation Index Expanded, Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.585-588
  • Keywords: Behcet's disease, infliximab, intracardiac thrombus, pulmonary embolism, INTRACARDIAC THROMBUS, INVOLVEMENT, ANEURYSMS, CRITERIA


Cardiac involvement is an uncommon and life-threatening complication of Behget's Disease. We present a 14-year-old boy, admitted to our hospital for recurrent hemoptysis. In his radiologic evaluation, a right ventricular thrombus and pulmonary arterial aneurysm were identified. He was diagnosed with Behcet's Disease, and then he received prednisone and cyclophosphamide. However, his cardiac thrombus enlargened. After his treatment was replaced with infliximab, the pulmonary aneurysms regressed, and the cardiac thrombus disappeared. In conclusion, infliximab should be considered as a reliable option for vascular Behcet's Disease resistant to conventional treatment.