Serum osteopontin and CD44 levels in lymphoreticular malignancies in children


Elli M., Dagdemir A., Bozkurt C., PINARLI F. G. , Duzgun A., Ozmen Z. C. , ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.113, no.9, pp.534-538, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 113 Issue: 9
  • Publication Date: 2012
  • Doi Number: 10.4149/bll_2012_120
  • Title of Journal : BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Page Numbers: pp.534-538

Abstract

Objective: Osteopontin (OPN) is an adhesive glycoprotein that interacts with a variety of cell surface receptors, including several integrins and CD44. OPN is expressed and secreted by numerous human malignancies. CD44 play an important role in tumor growth and metastasis. We aimed to evaluate serum levels of osteopontin and CD44 in patients with lymphorethicular malignancies in childhood.