Serum osteopontin and CD44 levels in lymphoreticular malignancies in children


Elli M., Dagdemir A., Bozkurt C., PINARLI F. G. , Duzgun A., Ozmen Z. C. , ...Daha Fazla

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.113, sa.9, ss.534-538, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 113 Konu: 9
  • Basım Tarihi: 2012
  • Doi Numarası: 10.4149/bll_2012_120
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Sayfa Sayıları: ss.534-538

Özet

Objective: Osteopontin (OPN) is an adhesive glycoprotein that interacts with a variety of cell surface receptors, including several integrins and CD44. OPN is expressed and secreted by numerous human malignancies. CD44 play an important role in tumor growth and metastasis. We aimed to evaluate serum levels of osteopontin and CD44 in patients with lymphorethicular malignancies in childhood.