Umbilical cord mesenchymal stromal cells engraft and transdifferentiate into cardiomyocyte-like cells following acute myocardial ischemia


Yigman Z. , Ozdemir E. D. , Turan N. N. , Ulus A. T. , CAN A.

ACTA HISTOCHEMICA, cilt.122, sa.6, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Objective: Human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs) gained importance in acute/chronic ischemic cardiomyopathy because of their outstanding regenerative potential in various pathologic conditions. The present study was designed to determine to what extent hUC-MSCs contribute to myocardial regeneration in acute experimental myocardial infarction (MI) in rats.